These are the recommended methods for enabling Trim in macOS:

macOS Version             App
Snow Leopard 10.6.8Trim Enabler 2
LionTrim Enabler 2
Mountain LionTrim Enabler 3
MavericksTrim Enabler 3
Yosemite 10.10.0 – 10.10.2Not supported, read more here
Yosemite 10.10.3 – 10.10.5Trim Enabler 4 or Disk Sensei
El CapitanTrim Enabler 4 or Disk Sensei
SierraTrim Enabler 4 or Disk Sensei
High SierraTrim Enabler 4 or Disk Sensei
MojaveTrim Enabler 4 or Disk Sensei
CatalinaTrim Enabler 4 or Sensei
Big SurTrim Enabler 4 or Sensei
MontereySensei

How to enable Trim on your Mac

You can get the correct app for your macOS version below.

Trim Enabler 2 / Trim Enabler 3

These are older version of Trim Enabler that is included when you purchase the latest Trim Enabler 4. You will receive instructions for downloading these older versions in your Trim Enabler order email.

Trim Enabler 4

You can download Trim Enabler 4 here: Get Trim Enabler.

Sensei

You can download Sensei here: Get Sensei.